Daniel Dubois and Anthony Joshua will contest the IBF heavyweight world title at Wembley Stadium on 21 September.
Over 80,000 fans are expected to attend as the British heavyweights collide.
Joshua will be aiming to become a three-time world champion while Dubois looks to retain the IBF title he is yet to win officially in the ring.
Belfast’s Anthony Cacace is also in action, defending his IBF super-featherweight title against Leeds’ Josh Warrington.
Live text commentary on the BBC Sport website and app will start at 20:00 BST on Saturday, 21 September.
Build-up will be available throughout fight week, including daily podcasts from the BBC Radio 5 Live Boxing team with Steve Bunce.
What time are the Dubois v Joshua ringwalks?
Ringwalks are expected to be late on the Saturday evening. A pattern has emerged at recent heavyweight fight nights of a late ringwalk.
In May, Fury and Usyk were standing in the ring waiting for the first bell at 23:45 BST, having made their ringwalks at around 23:30.
Similar timings are expected for Dubois v Joshua.
Who is on the undercard and what is the running order?
Main event: Daniel Dubois v Anthony Joshua (IBF heavyweight title)
Undercard:
Hamzah Sheeraz v Tyler Denny (European middleweight title)
Anthony Cacace v Josh Warrington (IBF super-featherweight title)
Joshua Buatsi v Willy Hutchinson (WBO interim light-heavyweight title)
Liam Smith v Josh Kelly (light-middleweight)
Mark Chamberlain v Josh Padley (lightweight)
*all 12x3min rounds as it stands
Which belts are on the line?
The IBF title is on the line in the headline fight at Wembley. Joshua is a previous long-time owner of the belt.
Dubois is technically the defending champion after Oleksandr Usyk’s decision to vacate the title following his win over Tyson Fury in May meant the Londoner was upgraded from interim champion to full champion status.
The winner is likely to be first in line to face the winner of Usyk’s rematch with Fury in December.
How do Dubois’ and Joshua’s records compare?
Joshua, 34, is vastly more experienced at world championship level than Dubois. He is a two-time unified world heavyweight champion having held every world title except the WBC belt in his career.
Dubois failed in his only world title challenge last year against Usyk and has never fought at Wembley Stadium. This will be Joshua’s third appearance at the venue and his sixth stadium fight overall.
Joshua has 12 world title fights under his belt, nine of those wins. The Londoner has won his last four fights in a row, three of those by stoppage.
Dubois, 26, has won his last two fights in a row since losing to Usyk in August 2023. Both men have an impressive knockout rate. Of Dubois’ 21 wins in 23 fights, 20 of those have come via knockout.
Joshua, in comparison, has 25 knockouts in 28 wins.
Dubois’ defeats have come to Usyk and Joe Joyce, while Joshua has lost to Usyk (twice) and Andy Ruiz Jr.