It was not clear at this point when the six were last seen.
Their bags were packed. Suitcases were found near the front door, the Bangkok Post reported.
The Grand Hyatt Erawan has over 350 rooms. It is located in a popular tourist district that is home to several upscale shopping malls and the Erawan shrine, a visitor draw.
WHAT’S THE FOCUS OF INVESTIGATIONS?
Thai authorities say there were no signs of robbery or assault. The room had not been ransacked. It was locked from the inside.
“The initial suspicion is that it might involve something ingested, based on the autopsy and forensic evidence,” said the Thai prime minister, who visited the hotel late on Tuesday with senior police officials.
“It is suspected that they have been dead for about 24 hours.”
The police also ruled out a suicide, without providing further explanation.
“What we can prove now is that they are not dead from suicide but from the killing of others,” said police chief Thiti.
From the fingerprint investigation, no outsiders had entered the room, he told reporters.
“It is possible that it occurred from the inside, possibly a hideout,” he said, adding that none of the six people had any injuries.